Global Challenges in Neglected Tropical Diseases

International Conference on

Global Challenges

in Neglected Tropical Diseases

July 13-15, 2016, León SPAIN
International Conference on

Global Challenges

in Neglected Tropical Diseases

July 13-15, 2016, León SPAIN

Welcome

"Conquer The Parasites"

Dear colleague,

Welcome to the first international conference on "Global Challenges In Neglected Tropical Diseases" to be held at León (Spain) on July 13 to 15, 2016.

León, the home of 13th-century Catedral de Léon and 10th-century Romanesque Basílica de San Isidoro, is a gateway city to beautiful North West Spain.

The parasites must be defeated through multidisciplinary Biology, Pathogenesis, Molecular Targets and New Drug/Vaccine Discovery approaches. This conference shall focus on current status of these efforts directed against treatment, control and elimination of neglected parasitic diseases. The following topics will be discussed:

Biology and pathogenesis of the pathogens, diseases and hosts.
Molecular targets-based and structure-based medicinal chemistry approach to maintain healthy drug-discovery pipelines.
Monitoring, containment and treatment of drug resistant cases.
Bench to bedside translational research to evaluate new drugs and drug combinations.
Socioeconomic and public awareness programs in neglected tropical parasitic diseases.
Opportunities to develop multidisciplinary programs and current funding opportunities

Neglected Tropical Parasitic Diseases: Facts and figures

The tropical parasitic diseases are responsible for staggering morbidity and millions of deaths every year, especially in the tropical regions of the World.
Although incidences of these diseases are mostly centered in tropical regions the socioeconomic and public health impacts of tropical parasitic diseases are global.
More than half of the world’s population is currently under the risk of being exposed to the infection with one or the other tropical disease pathogens.
Emergence and spread of drug-resistant and more virulent parasite strains have further intensified the problem.
Despite the heavy burden on humanity, the tropical parasitic diseases have been mostly ignored in relation to advances in modern drug discovery and only few new antiparasitic drugs have been developed during the last years.
This conference was conceived as a response to recent advances in this area that have been culminated in the current Nobel Prize in physiology or medicine in 2015.

Global Challenges

Significant increase in global business practices and leisure travel to the endemic counties require effective measures to protect the transient population from getting afflicted with the tropical parasitic diseases.

Improved global attention with increasing funding opportunities through public and non-profit organizations as well as emergence of public-private partnerships for the development of strategies to monitor, treat, control and eliminate neglected tropical parasitic diseases have generated unprecedented interests in new programs on discovery and development of drugs/vaccines.

This conference will combine excellent science, establishing new relationships and, why not, a recreational and cultural environment of the first order. We would like to encourage scientists from all over the world to actively participate in this conference.

Welcome to León!

On behalf of the organizing committee
Rafael Balaña Fouce
CU Ciencias Biomédicas
Director INBIOTEC (SPAIN)

ORGANIZERS

Jorge Alvar

DNDi

Jorge Alvar PhD, Head of Visceral Leishmaniasis, DNDi, was the director of the National Centre of Tropical Medicine at the Institute of Health Carlos III, Madrid (Spain) and the Medical Officer in charge of the Leishmaniasis Control Programme in the Department of Neglected Tropical Diseases at WHO (2004-2012). Dr. Alvar has considerable expertise in neglected diseases, and has received awards for, his research in leishmaniasis epidemiology, chemotherapy and diagnosis, canine infection, and AIDS co-infection.

Babu L Tekwani

NCNPR

Dr. Babu L. Tekwani PhD, Professor of Pharmacology at the University of Mississippi (UM, USA), Principal scientist at National Center for Natural Products Research and Coordinator of the UN/Walter Reed Army Institute Research Discovery Programme (USA). He is a renowned specialist in natural products drug discovery for malaria, trypanosoma and leishmania parasites.

Francisco Rojo

ULE

Rojo-Vázquez PhD, Full Professor of Parasitology at the Animal Health Department of Faculty of Veterinary Medicine, University of León (Spain). He has been Full Professor of Parasitology at Dpt. Parasitology of Faculty of Pharmacy of University of Salamanca (Spain) and University Complutense of Madrid (Spain). He has been Dean of Faculties of Pharmacy and Veterinary Medicine at Universities of Salamanca and León, respectively. In 2007, he was the Head of the Centre for Investigation in Animal Health, Spanish Ministry of Science and Innovation and Vice-principal for Research of the National Institute of Agricultural Research (Spanish Ministry of Science and Innovation). He has also been the President of the Spanish Society of Parasitology and Founding Diplomate of the European Veterinary Parasitology College (EVPC). He is member of the Spanish Academy of Veterinary Science.

Rafael Balaña

ULE

Rafael Balaña-Fouce PhD, Professor of Biomedical Sciences at the University of León (ULE, Spain) and Scientific Director of the Institute of Biotechnology of León (INBIOTEC). He has developed his scientific work in polyamines and topoisomerases from leishmania parasites. Part of his current work involves phenotypic-based platforms for drug discovery using optical readouts and screening of new compounds against Leishmania.

María Martínez

CSIC-ULE

María Martínez Valladares DVM, PhD, Researcher at the University of León (Institute of Mountain Livestock). Her main research projects are focused on the detection of anthelmintic resistances using in vivo and in vitro methods, the study of those mechanisms involved in the development of resistance and the search of new molecules with anthelmintic activity. On the other hand she is the CEO and founder of Solpax, a biotechnology company whose objective is the detection of vector borne diseases.

PROGRAM

Tropical Parasitic Diseases:
Biology, Pathogenesis, Molecular Targets and New Drug Discovery

13 July 2016

Session 1: Inaugural keynote

Place: Salón Pendón de Baeza

Welcome
4:00 pm Registration
5:30-6:00 pm Welcome message from the Council of Leon by Councillor for Culture, Heritage and Tourism (Miss Margarita Torres Sevilla)
6:00-7:00pm Keynote speaker: Dr. Gerald Spaeth, Département de Parasitologie et Mycologie Institut Pasteur, Paris, France "TARGETING HOST/PARASITE INTERACTION FOR ANTI-LEISHMANIAL DRUG DISCOVERY". Chairperson, Dr. Babu L. Tekwani
7:00-8:00pm Keynote speaker: Dr. Jorge Alvar, DNDi Geneva, Switzerland "ADVANCES IN VISCERAL LEISHMANIASIS TREATMENT: SUCCESSES, PITFALLS AND HOPES". Chairperson, Dr. Francisco A. Rojo Vázquez
8:00-9:00pm Guided tour to Old City of León.
9:00-10:00pm Opening Reception.

14 July 2016

Registration
Breakfast

Session 2: Biology and Pathogenesis

Chairperson: Dr. Manuel Fresno

Place: Salón Pendón de Baeza

8:30-9:10am PS-1: Dr. Dan Zilberstein, Technion Israel Institute of Science, Haifa, Israel "SIGNALING PATHWAYS IDENTIFIED BY SYSTEMS ANALYSIS OF LEISHMANIA DIFFERENTIATION".
9:10-9:35am IS-1: Dr. Birgitta Knudsen, Department of Molecular Biology and Genetics, Aarhus University, Denmark. "NEW TOOLS FOR DIAGNOSIS OF INFECTIOUS DISEASES".
9:35-9:50am IS-2: Luis Rivas López, Centro de Investigaciones Biológicas (CSIC) Madrid, Spain "IS THE LIPID MATRIX OF LEISHMANIA A DESPISED TARGET FOR CHEMOTHERAPY? A PEPTIDE-BASED APPROACH".
9:50-10:05am CS-1: Dr. Albert Descoteaux, INRS Institute Armand-Frappier, Laval Canada "TRAFFICKING OF LEISHMANIA VIRULENCE FACTORS WITHIN INFECTED MACROPHAGES".
10:05-10:20am CS-2: Dr. Christelle Cren-Travaillé, Institute Pasteur Paris (France) "HOW AFRICAN TRYPANOSOMES REMAIN TRANSMISSIBLE IN THE MAMMALIAN HOST?".
10:20-10:30am Dr. Una Ryan, School of Veterinary and Life Sciences, Murdoch University, Western Australia, Australia "APPLICATION OF PLATFORM TECHNOLOGIES TO THE DETECTION AND CHARACTERISATION OF CRYPTOSPORIDIUM".
10:30-10:40am Dr. María Pereira, Global Health and Tropical Medicine, Universidade Nova de Lisboa, Lisboa, Portugal "LEISHMANIA INFANTUM INFECTION: THE DOUBLE FACE OF DOG´S NEUTROPHILS".

10:40-11:20am Break.

11:20-12:20am Guided tour of San Isidoro.

Session 3: Global challenges & opportunities

Chairperson: Dr. Rosa M. Reguera

Place: Salón Pendón de Baeza

12:20-12:45pm IS-3: Dr. Pierre Dorny, Institute of Tropical Medicine, Antwert, Belgium "TAENIA SOLIUM CYSTICERCOSIS: CHALLENGES OF APPLYING NOVEL CONTROL TOOLS".
12:45-1:10pm IS-4: Dr. Critina Donini, Medicines for Malaria Venture, Geneva (Switzerland) "HOW CAN WE ACCELERATE DRUG DEVELOPMENT THROUGH INNOVATIVE PHASE I AND PROOF OF CONCEPT STUDIES?".
1:10-1:25pm CS-3: Dr. Guadalupe Miró, Dpt. Sanidad Animal, Universidad Complutense de Madrid, Madrid, Spain "CANINE AND FELINE LEISHMANIOSIS: CURRENT STATUS IN EUROPE".
1:25-1:40pm CS-4: Dr. Marisol Arias, Faculty of Veterinary Medicine, University of Santiago de Compostela, Lugo, Spain "ELIMINATING THE RISK OF FOODBORNE TREMATODOSES BY MEANS OF THE OVICIDE FUNGUS MUCOR CIRCINELLOIDES".
1:40-1:50pm Dr. Estefania Calvo-Álvarez, Institute Pasteur, Paris, France "FROM THE FLY TO THE HOST: SENSING IN AFRICAN TRYPANOSOMES".

1:50-3:30pm Lunch and Break

Session 4: New Drug Discovery

Chairperson: Dr. Babu L. Tekwani

Place: Salón Pendón de Baeza

3:30-4:10pm PS-3: Dr. Vincent O'Connor, Professor of Neuroscience. Centre for Biological Sciences. University of Southampton "THE NOVEL CYCLO-OCTADEPSIPEPTIDE ANTHELMINTIC EMODEPSIDE; MODE OF ACTION AND SPECTRUM OF ACTIVITY".
4:10-4:35pm IS-5: Manu de Rycker, Drug Discovery Unit, University of Dundee | Dundee DD1 5EH | UK "DISCOVERY AND LEAD-OPTIMISATION OF A PROMISING NEW ANTILEISHMANIAL COMPOUND SERIES WITHIN AN ACADEMIC-INDUSTRY PARTNERSHIP".
4:35-5:00pm IS-6: Dr. Arturo San Feliciano, Dpt. Pharmaceutical Chemistry, University of Salamanca, Spain "DISCOVERY OF NEW MOLECULES AGAINST NTDs THE USAL EXPERIENCE".
5:00-5:25pm IS-7: Dr. Rosa M. Reguera, Dpt. Biomedical Sciences, University of León, León, Spain "A DRUG DISCOVERY “EX VIVO” PLATFORM AGAINST VISCERAL LEISHMANIASIS".

Session 4 (Parallel 1): New Drug Discovery

Chairperson: Dr. Rafael Balaña Fouce

Place: Salón San Isidoro

6:00-6:15pm CS-5: Dr. Juan Cantizani, Molecular Discovery ResearchGSK Tres Cantos, Madrid (Spain) "GSK MOLECULES AND MODELS TO FIND NEW ANTI-LEISHMANIAL DRUGS".
6:15-6:30pm CS-6: Dr. Nestor Carballeira, Department of Chemistry, University of Puerto Rico, San Juan, Puerto Rico, USA. "NATURAL MARINE AND TERRESTRIAL LIPIDS AS NEW AGENTS AGAINST LEISHMANIASIS".

6:30-6:40pm Dr. Concepción Alonso, Dpt. de Química Orgánica I, Universidad del País Vasco, Vitoria-Gasteiz, Spain "DESIGN AND SYNTHESIS OF TOPOISOMERASE I INHIBITORS WITH ANTILEISHMANIAL ACTIVITY".
6:40-6:50pm Dr. Jan Carlo Delorenzi, Hebron Pharmaceutical Group, Mackenzie Presbyterian University, Sao Paulo, Brazil "18-METHOXYCORONARIDINE (18-MC): INNOVATIVE ORAL DRUG FOR LEISHMANIASIS TREATMENT"

Session 4 (Parallel 2): New Drug Discovery

Chairperson: Dr. María Martínez Valladares

Place: Salón Pendón de Baeza

6:00-6:10pm Dr. Marisol Arias, Faculty of Veterinary Medicine, University of Santiago de Compostela, Lugo, Spain "AN APPROACH TO PREVENT CUTANEOUS LARVA MIGRANS BY A SUSTAINABLE STRATEGY".
6:10-6:20pm Aikaterini Lalatsa, School of Pharmacy and Biomedical Sciences, University of Portsmouth, UK "ORAL NANOMEDICINES FOR THE TREATMENT OF PARASITIC DISEASES".
6:20-6:30pm Dr. Dolores R. Serrano Dpt Farmacia y Tecnologia Farmaceutica, Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain "ENGINEERING SYNERGISTICALLY ACTIVE AND BIOAVAILABLE COST-EFFECTIVE MEDICINES FOR NEGLECTED TROPICAL DISEASES; THE ROLE OF EXCIPIENTS".
6:30-6:40pm Dr. Rosario Díaz, Instituto de Parasitología y Biomedicina "López-Neyra" CSIC, Granada, Spain "DRUGGING PARASITE KINOME: FROM COMPOUND REPURPOSING TO HIT-TO-LEAD DISCOVERY FOR SLEEPING SICKNESS".
6:40-6:50pm Dr. Rocio Paucar, Dpt. Organic Chemistry. Institute of Tropical Health, University of Navarra Pamplona, Spain "IN VITRO AND IN VIVO ANTI-TRYPANOSOMA CRUZI ACTIVITY OF NEW ARYLAMINE MANNICH BASE DERIVATIVES".

7:00-8:00pm San Isidoro's Museum guided tour.

8:00-9:00pm Dinner

15 July 2016

Keynote Conference

Place: Salón Pendón de Baeza

8:30-9:30am Keynote speaker: Dr. Carlos Lanusse, Centro de Investigación Veterinaria de Tandil (CIVETAN) Argentina "CHALLENGES TO OPTIMIZE THE ACTIVITY AND EXTEND THE LIFESPAN OF ANTHELMINTIC MOLECULES IN THE PRESENCE OF RESISTANT HELMINTH POPULATIONS". Chairperson: Dr. Francisco A. Rojo Vázquez

Session 5: Multiomics

Chairperson: Dr. Rosario Díaz González

Place: Salón Pendón de Baeza

9:30-10:10am PS-4: Dr. Marc Ouellette, Centre de Recherche en Infectiologie du Centre De Recherche, Université Laval, Québec, Canada "GENOMICS OF DRUG RESISTANCE IN LEISHMANIA".
10:10-10:35am IS-8: Dr Cinzia Cantacessi, Department of Veterinary Medicine.University of Cambridge, Cambridge CB3 0ES, UK "SUPPRESSION OF INFLAMMATION BY HELMINTHS – A ROLE FOR THE GUT MICROBIOTA?".
10:35-10:50am CS-7: Dr. Martin Olivier, Research Institute of McGill University Health center, Montreal (Canada) "LEISHMANIAL SANDFLY VECTOR NANOBIOME: IMPACT ON CUTANEOUS LEISHMANIASIS".
10:50-11:05am CS-8: Dr. Eva Rico, Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK "GENOME-WIDE SELECTIVE SCREEN IDENTIFIES A NEGATIVE REGULATOR OF TRANSMISSION STAGE-ENRICHED MEMBERS OF THE TRYPANOSOMA BRUCEI CELL SURFACE PHYLOME".
11:05-11:40am Break

Session 6: Molecular Targets

Chairperson: Dr. Estefanía Calvo Álvarez

Place: Salón Pendón de Baeza

11:40am-12:10pm PS-5: Dr. Luis Ignacio Álvarez, Centro de Investigación Veterinaria de Tandil (CIVETAN), Argentina "PHARMACOKINETIC-PHARMACODYNAMIC RELATIONSHIPS OF ANTHELMINTIC DRUGS".
12:10-12:35pm IS-9: Dr. Una Ryan, School of Veterinary and Life Sciences, Murdoch University, Western Australia, Australia "TARGET VALIDATION OF THE INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) GENE IN CRYPTOSPORIDIUM USING PHYLOMER PEPTIDES".
12:35-12:50pm CS-9: Dr. Bárbara Papadopoulou, Centre de Recherche en Infectiologie, Université Laval, Québec, Canada "RNA-BINDING PROTEINS CONTROLLING LEISHMANIA INTRACELLULAR DEVELOPMENT".
12:50-13:05pm CS-10: Dr. Melissa L. Sykes, Eskitis Institute for Drug Discovery, Griffith University, Nathan, Australia "SELECTION OF COMPOUNDS FOR TARGET STUDIES IN THE UTILIZING IMAGINE AND REDOX BASED".
13:05-13:20pm Dr. Monika Gulia-Nuss, University of Nevada, Reno, USA "ROLE OF MOSQUITO INSULIN SIGNALING IN PARASITE DEVELOPMENT".

13:40-15:30pm Lunch and Break

Session 7: Drug Resistance and Translational Research

Chairperson: Dr. María Martínez Valladares

Place: Salón Pendón de Baeza

3:30-4:10pm PS-6: Dr. Manuel Fresno, Centro de Biología Molecular Severo Ocho (CSIC) Madrid, Spain "UNDERSTANDING THE COMPLEX IMMUNOPATHOGENESIS OF TRYPANOSOMA CRUZI INFECTION".
4:10-4:35pm IS-10: Dr. Francisco Rojo , Dpt. Animal Health, University of León, León Spain "INTEGRATED CONTROL OF SOME HELMINTH INFECTIONS OF ANIMALS AND MEN".
4:35-5:00pm IS-11: Dr. Jürgen Krücken, Institute for Parasitology and Tropical Veterinary Medicine Freie Universität, Berlin, Germany "ANTHELMINTIC RESISTANCE RESEARCH IN VETERINARY PARASITOLOGY AS A BLUE PRINT TO TACKLE AN EMERGING ISSUE IN HUMANS?".
5:00-5:15pm CS-11: Dr. Harry De-Koning, University of Glasgow, Glasgow, UK "HIGHLY CONSERVED TRANSPORTER FAMILIES INVOLVED IN HIGHLY SPECIFIC DRUG TRANSPORT IN KINETOPLASTID PARASITES".
5:15-5:30pm CS-12: Dr. Richar Rodríguez-Hidalgo, Centro Internacional de Zoonosis, Universidad Central del Ecuador, Quito, Ecuador "FIRST REPORT OF ACARICIDE RESISTANCE (AMITRAZ, ALPHA-CYPERMETHRIN AND IVERMECTIN) ON RHIPICEPHALUS MICROPLUS IN ECUADOR".
5:30-5:40pm Dr. Laura González, Biología y control de enfermedades Infecciosas, Universidad de Antioquia, Antioquía, Colombia "ALCOHOL DEHYDROGENASE AND ALDO-KETO REDUCTASE ARE INVOLVED IN THE MECHANISM OF RESISTANCE TO BENZNIDAZOL TRYPANOSOMA CRUZI".

Session 8: Concluding keynote

Chairperson: Dr. Rafael Balaña Fouce

Place: Salón Pendón de Baeza

6:30-7:30pm Concluding conference: Dr. Babu L. Tekwani, National Center for Natural Products Research, Mississippi USA "NEW ANTIPARASITIC DRUG DISCOVERY FROM NATURAL PRODUCTS: CHALLENGES AND OPPORTUNITIES".

9:00-11:00pm Closing Banquet and Awards

Some information of León

Population

Km2 of province

Tourists a year

Bars and restaurants

VENUE

San Isidoro Royal Collegiate Hotel. León (Spain)

The Congress will take place entirely in the Collegiate Church of San Isidoro within a historical and artistic context of exceptional value. León is a historical city in the Northwest of Spain with a unique historical setting including the place where true Holy Grail is exhibited. This is well connected by high-speed trains (AVE) from Madrid and has an airport with daily flights from Barcelona. Quality of its gastronomy is broadly recognized.

The University of León with two campuses (León and Ponferrada) and is leader in research institutes. Agricultural, Pharmaceuticals and Biotechnological enterprises have characterized the region for decades.

Accommodation

HOTEL REAL COLEGIATA

Single room breakfast included: 54 €
Double room for single use breakfast included: 54 €
Double room breakfast included: 62 €

Prices with VAT included. Telephone for booking: +34 987875088.

HOTEL QUINDÓS

Single room breakfast included: 37 €
Double room for single use breakfast included: 45 €
Double room breakfast included: 48 €

Prices with VAT included. Telephone for booking: +34987236200.

HOTEL SAN MARCOS

Single room breakfast included: 85 €
Double room breakfast included: 120 €

Prices with VAT included. Telephone for booking: +34987237300.

HOTEL CONDE LUNA

Double room for single use breakfast included: 60 €
Double room breakfast included: 70 €

Prices with VAT included. Telephone for booking: +34987206512.

HOTEL ALFONSO V

Double room for single use breakfast included: 60 €
Double room breakfast included: 70 €

Prices with VAT included. Telephone for booking: +34987220900.

RESIDENCIA EMILIO HURTADO

Triple use apartment: 16,34 € (per person and day)
Doble use apartment: 17,82 € (per person and day)
Single use apartment: 30,60 € (per person and day)

Telephone for booking: +34987223434. Email for booking: informacion@rehurtado.com. Identify yourself as a participant in the congress.

Welcome

"Conquer The Parasites"

ORGANIZERS

Jorge Alvar

DNDi

Babu L Tekwani

NCNPR

Francisco Rojo

ULE

Rafael Balaña

ULE

María Martínez

CSIC-ULE

Sponsors

with the collaboration and sponsorship of

PROGRAM

Tropical Parasitic Diseases: Biology, Pathogenesis, Molecular Targets and New Drug Discovery

Session 1: Inaugural keynote

Place: Salón Pendón de Baeza

Session 2: Biology and Pathogenesis

Place: Salón Pendón de Baeza

Session 3: Global challenges & opportunities

Place: Salón Pendón de Baeza

Session 4: New Drug Discovery

Place: Salón Pendón de Baeza

Session 4 (Parallel 1): New Drug Discovery

Place: Salón San Isidoro

Session 4 (Parallel 2): New Drug Discovery

Place: Salón Pendón de Baeza

Keynote Conference

Place: Salón Pendón de Baeza

Session 5: Multiomics

Place: Salón Pendón de Baeza

Session 6: Molecular Targets

Place: Salón Pendón de Baeza

Session 7: Drug Resistance and Translational Research

Place: Salón Pendón de Baeza

Session 8: Concluding keynote

Place: Salón Pendón de Baeza

Some information of León

Population

Km2 of province

Tourists a year

Bars and restaurants

VENUE

San Isidoro Royal Collegiate Hotel. León (Spain)

Accommodation

HOTEL REAL COLEGIATA

Single room breakfast included: 54 € Double room for single use breakfast included: 54 € Double room breakfast included: 62 €

HOTEL QUINDÓS

Single room breakfast included: 37 € Double room for single use breakfast included: 45 € Double room breakfast included: 48 €

HOTEL SAN MARCOS

Single room breakfast included: 85 € Double room breakfast included: 120 €

HOTEL CONDE LUNA

Double room for single use breakfast included: 60 € Double room breakfast included: 70 €

HOTEL ALFONSO V

Double room for single use breakfast included: 60 € Double room breakfast included: 70 €

RESIDENCIA EMILIO HURTADO

Triple use apartment: 16,34 € (per person and day) Doble use apartment: 17,82 € (per person and day) Single use apartment: 30,60 € (per person and day)

Presentation guidelines

Oral Presentations:

Poster Presentations:

Submission of Abstracts

Organization of the abstract

The presentations will be assigned to one of the following scientific sessions.

Only the abstracts with registration fees paid by April 30, 2016 would be considered for publication and inclusion in the final program.

CONTACT

SCIENTIFIC SECRETARY

Rafael Balaña Fource

Babu L. Tekwani

TECHNICAL SECRETARY

Fundación General Universidad de León y Empresa

Facebook Page

Tropical Parasitic Diseases:
Biology, Pathogenesis, Molecular Targets and New Drug Discovery

Single room breakfast included: 54 €
Double room for single use breakfast included: 54 €
Double room breakfast included: 62 €

Single room breakfast included: 37 €
Double room for single use breakfast included: 45 €
Double room breakfast included: 48 €

Single room breakfast included: 85 €
Double room breakfast included: 120 €

Double room for single use breakfast included: 60 €
Double room breakfast included: 70 €

Double room for single use breakfast included: 60 €
Double room breakfast included: 70 €

Triple use apartment: 16,34 € (per person and day)
Doble use apartment: 17,82 € (per person and day)
Single use apartment: 30,60 € (per person and day)